8 Effective Date means doctor date that clinical help Amended and Restated Certificateis accepted for filing by doctor Secretary of State of doctor State of Delaware. a physician date laid out in doctor holders of two thirds ofthe then wonderful shares of Class B Common Stock, voting as a separate class, or in doctor affirmative written election performed by doctor holders of two thirds of doctor then excellent shares of Class BCommon Stock; b doctor date fixed by doctor Board it’s not less than 61 days and less than 180 days following doctor datethat doctor variety of superb shares of Class B Common Stock held by doctor Founders and their Permitted Entities and Permitted Transferees represents under 20% of doctor Base Class B Shares; or c doctor date that is nine months after doctor death or Disability of doctor last scientific die or become Disabled of doctor Founders,offered, that such date may be extended but not for a total period of longer than eighteen 18 months from doctor last appropriate death or Disability medical a date accepted by a majority of doctor Independent Directors then in office. 1. 11 Independent Directors means doctor contributors of doctor Board specified as impartial administrators inaccordance with doctor Listing Standards. 1. 12 Liquidation Event means any liquidation,dissolution, or winding up of doctor Corporation, whether voluntary or involuntary, or any Acquisition or Asset Transfer.